DIFFERENTIAL AFFINITY CHROMATOGRAPHY COUPLED TO MASS SPECTROMETRY: A SUITABLE TOOL TO IDENTIFY COMMON BINDING PROTEINS OF A BROAD-RANGE ANTIMICROBIAL PEPTIDE DERIVED FROM LEUCINOSTATIN

Differential Affinity Chromatography Coupled to Mass Spectrometry: A Suitable Tool to Identify Common Binding Proteins of a Broad-Range Antimicrobial Peptide Derived from Leucinostatin

Leucinostatins are antimicrobial peptides with a broad range of activities against infectious agents as well as mammalian cells.The leucinostatin-derivative peptide ZHAWOC_6027 (peptide 6027) was tested in vitro and in vivo for activity against the intracellular apicomplexan parasite Toxoplasma gondii.While highly efficacious in vitro (EC50 = 2 nM)

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Opinion control in complex networks

In many political elections, the electorate appears to be a composite of partisan and independent voters.Given that partisans are not likely to convert to a different party, an important goal for a political party could be to mobilize independent voters toward the party with the help of strong leadership, mass media, partisans, and the effects of p

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